![]() Chronic kidney disease (CKD) – a longstanding disease of the kidneys leading to renal failure.Health Risks Associated with Proton Pump Inhibitorsīy blocking the creation of gastric acids in the stomach, PPIs can also block the absorption of minerals into the body. Therefore the FDA has recommended no more than three 14-day treatment courses in a one-year time period. However, upon closer study, researchers determined that while the short-term side effects were minimal, there was a slew of possible long-term health risks that could develop. Proton pump inhibitors gained traction as a remedy for heartburn since they have minimal short-term side-effects, including: Gastrinomas – A tumor in the pancreas or duodenum that secretes an excess of gastrin, leading to ulceration in the duodenum, stomach, and small intestine. ![]() Zollinger-Ellison Syndrome – A condition in which one or more tumors form in your pancreas or the upper part of your small intestine.Peptic Ulcer Disease (PUD) – A sore that develops on the lining of the esophagus, stomach, or small intestine.Gastroesophageal Reflux Disease (GERD) – A digestive disease in which stomach acid or bile irritates the food pipelining.Gastritis – Any group of conditions in which the stomach lining is inflamed.Barrett's Esophagus – Damage to the lower portion of the tube that connects the mouth and stomach.Proton pump inhibitors have also been used to help with a myriad of other medical conditions such as: The primary function of a proton pump inhibitor is to reduce the production of gastric acid which, in turn, helps reduce the heartburn the acid can cause. Some of the other popular PPI drugs include: The most popular of these PPI drugs would be Prilosec (omeprazole) and Nexium (esomeprazole) with $218 million - $300 million dollars in annual sales respectively. Proton pump inhibitor drugs are available over the counter or by prescription as a pill or liquid ingested orally. Find out the dangerous side effects of heartburn medications and what legal rights you have. Alas, proton pump inhibiting drugs have been linked to chronic kidney disease and kidney failure, among other health issues. Proton pump inhibitors are taken by an estimated 15 million Americans and rake in around 10 billion dollars annually.Īs such a commonplace heartburn remedy, one would assume it would be completely safe. Proton pump inhibitors are among the more commonly used heartburn drugs you can get over the counter or via prescription today. Dangerous Side Effects of Heartburn Medications PPI Drugs Can Cause Kidney Damage and Disease
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